re: Vitamin D Deficiency Prevalent in Epilepsy Patients

Anathema — Tue, 11 Dec 2007 22:04:05 GMT

I read somewhere that vit D3 needs an p450 enzyme in the
liver and kidneys in order to be synthesized. So the vit D
deficiency theory(as well as other vitamin deficiencies) may truly go
back to the p450 system, perhaps not a deficiency in the sense
of lacking in the diet. Many ASD kids have issues with the p450 system and sulfation so they may be truly D deficient, but not necessarily because they aren't getting enough summer sun or vitamins. People could be prone to autoimmune diseases, etc not purely because of diet, but because something is damaging the p450 (mercury? estrogen?) system so they can't synthesize the D as well.
Also, while some seizure meds inhibit absorption of certain vitamins,sometimes this can be a possible mechanism of controlling the seizures. My child's meds inhibit calcium (and glutamate and other things...). If a person's calcium ion channels are dysfunctional then this would make them prone to an excitatory state. In this light, inhibiting the calcium would be a likely function of the med, not a side effect. The same for glutamate too. In fact, if I were to supplement calcium while on the med, it would lower the seizure threshold. The unfortunate side effect of calcium inhibition is that it reduces availability for other processes of course, but it's a devil's choice I've had to make. Seizures or deficiency? Because I know for sure my child has sulfation issues (see p450), I largely believe my child would still have epilepsy if supplemented vit D. I also believe I would see improvements in the summer when the best sun is at its peak.

These are just different possible ways of interpreting these results.

re: Vitamin D Deficiency Prevalent in Epilepsy Patients

Russ Bianchi — Tue, 11 Dec 2007 00:19:34 GMT

Sunshine will be endorse for medical replacement of bad for you reactive and drug protocols when Big Pharma has a way of metering the Sun.