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Less than 1 Percent of Human Obesity Due to Genetics

Posted By Dr. Mercola | January 18 2010 | 803 views
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Large-scale genome-wide association studies have identified 12 genetic loci that are robustly associated with body mass index (BMI).

However, effect sizes of the risk alleles were very small, ranging between 0.058 and 0.329 for BMI and between 0.094 and 0.866 kg for weight. On average, each additional risk allele was associated with an increase of 0.149 in BMI.

All of the genetic loci combined explained just 0.9 percent of BMI variation. Their predictive value for obesity risk is limited.

Sources:

  American Journal of Clinical Nutrition October 7, 2009; 91: 184-190
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Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.

†The World's #1 Natural Health Website claim is based upon Alexa Natural Health Website rankings.

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