Omega-6 Fats Promote Prostate Cancer Growth

Another reason men, and women, need to right-size the levels of omega-3 and omega-6 fats in their diets: The omega-6 fats contained in corn oil and other products may promote the growth of prostate cancer, according to a new study.

Working with human prostate cancer cells in tissue cultures, researchers found omega-6 fatty acids, added to the mix, spur the production of cPLA2, which then causes the production of the enzyme COX2. The introduction of COX2 stimulates the release of PGE2, a hormone-like molecule that promotes cell growth. Simply put, if you're eating a diet that's high in omega-6 fats, you could be vulnerable not only to prostate cancer, but colorectal and some breast cancers as well, scientists said.

Interestingly, the incidence of prostate cancer over the past 60 years has risen as dietary ratios of omega-3 and 6 fats have changed. Back at the end of World War II, omega-3 and omega-6 ratios were lopsided (1:2) in favor of omega-3s. Now, that ratio is 25:1 on the omega-6 side.

The downside of the study is a recommendation that new and unnecessary drugs be concocted to ward off prostate cancer based on the effect of flurbiprofen, a non-steroidal anti-inflammatory drug commonly prescribed for arthritis, that blocked the production of cPLA2 and broke the chain leading to cell growth. As you know, you don't need a toxic drug at all to prevent prostate cancer. Among the natural tools at your disposal:

I also recommend reviewing the advice of prostate cancer expert Dr. Larry Clapp.

Carcinogenesis May 5, 2005

Medical News Today August 2, 2005

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