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How Antidepressants Affect Your Immune System

A few months ago, an insightful report in the British Medical Journal argued brilliantly that antidepressants offer no meaningful benefit and emotional problems can be better handled without taking a toxic drug. Here's another health-harming reason to stay away from them: Antidepressants may affect your immune system too.

Antidepressants like Prozac work to blunt depression by allowing serotonin to linger around nerve junctions in the brain. Serotonin, according to new research, has another important function, as a signaling molecule between dendritic and T cells, two kinds of immune cells.

Dendritic cells pick up serotonin where inflammation arises, then passes it on to T cells that influence the development of new cells. Treating those cells with Prozac blocked the movement of serotonin from dendritic to T cells.

More evidence you should be avoiding antidepressants altogether, and using safer, healthier options that have nothing at all to do with taking a pill, to treat the true cause of your problem.

Blood, Vol. 107, No. 3, February 1, 2006: 1010-1017

Yahoo News January 27, 2006

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