Why Take an Antidepressant to Treat IBS?

Seemingly, researchers are forever in search of new and exotic uses for old, toxic drugs like antidepressants, in spite of the side effects. The latest abysmal use of serotonin selective reuptake inhibitors (SSRIs): Reducing the abdominal problems associated with irritable bowel syndrome (IBS).

Researchers compared the effect of citalopram (Celexa) at 20 and 40 mgs. for three weeks apiece to a placebo on 23 patients (who weren't suffering from depression) over two six-week treatments separated by a three-week gap.

No surprise, citalopram alleviated several IBS symptoms, including abdominal pain and bloating, as well as improving a patient's "overall well being." That good news flies in the face of a year-old FDA mandate, however, that slapped a stronger warning label on citalopram among 10 SSRIs, citing grave concerns about deepening depression and an elevated risk of suicide.

Some safer ways to treat IBS without a toxic SSRI:

Gut, Vol. 55, No. 8, August 2006: 1095-1103

Medscape July 26, 2006 Registration Required

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