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Vitamin D Works Better With Food

Many patients treated for vitamin D deficiency fail to achieve an adequate serum level of 25-hydroxyvitamin D despite high doses cholecalciferol. New research shows that administering vitamin D with the largest meal of the day will improve absorption and increase serum levels of 25OHD

The study looked at 17 patients at the Cleveland Clinic Foundation Bone clinic for treatment of vitamin D deficiency who were not responding to treatment.  After three months, their 25-hydroxyvitamin D had significantly improved.

The study’s authors concluded that taking vitamin D with the largest meal improves absorption and results in about a 50 percent increase in serum levels. Similar increases were observed in a wide range of vitamin D doses taken for a variety of medical conditions.