Fat Causes Chemical Changes in DNA

New research shows that fat appears to associate with distinctive chemical changes in DNA. This finding could help explain why obesity can increase the risk for chronic illnesses such as cardiovascular disease and diabetes.

Fat was at one time viewed as little more than padding and a ready energy source. However, scientists are learning that it more closely resembles a factory that makes chemicals and compounds such as hormones and proteins.

According to Eurekalert:

"Studies comparing two groups of obese versus lean teens found higher levels of chemical change, or methylation, in a portion of the UBASH3A gene and lower levels in part of the TRIM3 gene. Both genes are known to have roles in regulating the immune system, which is often dysregulated in obese individuals. Dysregulation can result in a level of chronic inflammation that contributes to diseases".

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