re: Coronavirus Antibodies May Last Only Three Months

datadragon — 6/20/2020 7:29:35 AM

Regarding the timeframe for how long antibodies may last. A study from Singapore released in April found that there were “significant levels of neutralizing antibodies in recovered SARS patients 9–17 years after initial infection.” The finding of neutralizing antibodies in SARS survivors 9–17 years after the initial infection is significant in the context of better understanding the longevity of SARSr-CoV protective immunity in general and vaccine development for SARS-CoV-2. www.tandfonline.com/.../22221751.2020.1761267

Vitamin A is important in antibody production. This study was done in China where approximately 87% of adults consumed less vitamin A than the Chinese Estimated Average Requirement (EAR), and only 6% of adults consumed more than Chinese Recommended Nutrient Intake (RNI). Chinese adults derived vitamin A mainly from plant source foods, which is supplied as carotenes (67.4% RE or 56.4% RAE). nutritionj.biomedcentral.com/.../s12937-018-0369-3 Converting beta carotene to vitamin A is also extremely variable and estimated that almost half of everyone have variants the BCMO1 gene which cause a 30-70% decrease in the amount of vitamin A that we can convert from beta-carotene. Zinc is also found low. www.ncbi.nlm.nih.gov/.../PMC5986452

CD8 T-cell responses. T-cells can determine what cells have been infected with a virus (because of peptides presented on the surface) and it blasts them with a cocktail of proteins that basically tell the cell to shut itself down immediately and kill itself because it's infected. Many viral pathogens are contained because after a T-cell mediated response you form long term T-cell memory. Those cells can persist for a lifetime. When you experience a pathogen your T-cells have fought off before, you get a much quicker expansion of T-cells and they are more potent at killing.

re: Coronavirus Antibodies May Last Only Three Months

Kitera — 6/19/2020 2:16:53 PM

That is unlikely to stop big pharna profits

will be interesting to see what measures are used to make people g4t the vaccine