re: Reduced Fat Milk Has a Greater Link to Childhood Obesity

datadragon — 1/17/2020 7:57:39 AM

Grass Fed Butter is one of the best sources of butyrate and to lesser extent, other foods that contain some dairy fat. The fattier the food, the more butyrate it will have, so whole organic or raw milk has more than skim milk, and heavy cream has more than either. Its one of the reasons why full-fat dairy is actually associated with lower BMI. Butyrate is shown it provides benefits for fighting chronic illnesses, such as diabetes, obesity, autism, ibd, leaky gut, autoimmunity and many forms of cancer including colon and breast among others. Gut flora can also make it provided you eat enough fiber and good gut flora isnt decimated (do a oat test) or lacking nutrients such as zinc and Vitamin A which alters gut microbiota composition and function. Research shows that butyrate production and the ability to produce butyrate are lower in Vitamin A and Zinc deficient mice and are needed for the anti inflammatory pathways to work. Eating fiber increases production of butyrate, which might be one of the reasons why fiber intake is so strongly associated with reductions in inflammation and improvements in gut health. It’s not the fiber per se; it’s the butyrate that your gut flora make with it. CLA is also in milk.

The most studied anti-inflammatory pathway of butyrate is via the inhibition of nuclear factor kappa B (NF-kB). This pathway controls the expression of genes encoding pro-inflammatory cytokines, inflammation-inducing enzymes, growth factors, heat shock proteins, and immune receptors. The anti-inflammatory properties of butyrate have been shown to be mediated by several mechanisms. including: the reduction of pro-inflammatory cytokine expression (interferon gamma [IFN-γ], tumor necrosis factor-α [TNF-α], interleukin-1B [IL-1B], IL-6, IL-8), the induction of IL-10 and transforming growth factor-B (TGF-B) expression and signaling, the induction of nitric oxide synthase and metalloproteinases, and the reduction of lymphocyte proliferation and activation.