Yahoo Finance lists 6 problems anyone with a desk job should be on the lookout for:
Carpal Tunnel Syndrome
Repeated motion can cause injury or pain. Stretching and other exercises may help release tension in your wrist.
Lower-Back Pain
Sitting for hours on end can be harmful to your body over time. Abdominal strengthening activities should relieve some of the pressure on your lower back.
Joint Problems
Staying in one position for too long can make joints tight. There are a number of stretches that can help loosen up your hips.
Eyestrain
If you spend hours a day staring at a computer screen, your vision gets blurry and your eyes become more sensitive. Increase your font size and rest your eyes frequently.
Bacteria
Your desk, in terms of bacteria, is 400 times more dirty than your toilet. Make sure to clean it, especially if you frequently eat your lunch at your desk.
Stressful Situations
Stress can always be a problem at work. Some stressors can be handled with breathing and relaxation techniques, but some conflicts may call for mediation.