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Mysterious Hormone's Role in Successful Weight Loss

  • April 03, 2004

Nearly four years ago I posted articles on leptin, the mysterious hormone that helps govern hunger and satiety. When it is released by fat cells into the bloodstream, leptin works to suppress appetite. A deficiency of the hormone leads to overeating and obesity. However, hopes for easily losing weight by simply taking leptin have not been borne out by human experiments. It appears leptin, which is produced by fat cells, plays a crucial role in establishing the brain's circuitry before...