Depo-Provera Gets The Black Box Treatment

On the heels of one black box warning by the FDA comes another. The injectable contraceptive Depo-Provera will now come with a special warning that links prolonged use of the drug with significant bone density loss. The FDA's decision to add such a warning followed analyses by the agency and Pfizer of data about the drug's long-term effect on bone density among teens and adult women. The drug maker claims, however, bone density loss has been "at least partially reversible" in girls and...

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