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Off-Label Use For Thalidomide as a Cancer Drug Questioned

  • December 21, 2004

A month ago, I posted a blog item about the FDA strenghtening the "X classification" on accutane to prevent pregnant women from taking the drug, which can cause serious fetal abnormalities. The plan, slated to be activated next summer, mirrors a similar program that prevented pregnant women from taking thalidomide some 45 years ago. Thalidomide wasn't sold in the United States until six years ago, when the FDA approved it to treat leprosy and as an off-label cancer treatment. A group...
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