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What Is Fisetin? Product Found in Fruits and Vegetables May Slow Aging, Researchers Show

Analysis by Dr. Joseph Mercola

A naturally-occurring byproduct of fruits and vegetables called fisetin may be a key to helping you slow the aging process by as much as 10 percent, Newsweek reports. New research shows that fisetin “very selectively and effectively kills” senescent cells that contribute to aging, according to the senior author of this particular study. In the laboratory, fisetin delivered directly to human fat tissue was able to reduce senescent cells there, but researchers cautioned more research is needed to determine the amounts of fisetin necessary to achieve similar results in a human body.

The search for youth in our old age is an ongoing endeavor as we try to figure out not only how to live longer, but to be as youthful and healthy in our old age as possible, for a longer period of time. Many researchers have gone so far as to declare aging a foundational disease that needs to be addressed if you want to prevent degenerative and chronic diseases.

Along that line, senescent cell research is not new: Previous studies show that senescent or nondividing cells play a significant role in the aging process. In fact, in mouse studies, researchers have discovered that removing senescent cells from their bodies profoundly extended their health span, allowing them to remain healthy and disease-free.

The bottom line is, if there's ever a pill that will ensure extended youth, everyone will likely want it. The question is whether or not such a thing is even possible. The fact of the matter is, your lifestyle and the choices you make every day play an incredible role in how you will age, and I doubt a drug will ever be devised that will allow you to be a junk food-eating couch potato and still age in reverse.

Of crucial importance is keeping your mitochondria healthy, and lifestyle strategies such as diet and exercise are key for this. Indeed, that’s the premise of my book, “Fat for Fuel,” and my upcoming book, “Superfuel,” both of which explain how efficient fat burning minimizes mitochondrial damage.

In short, high-carb, processed food diets prevent your body from efficiently burning fat as its primary fuel, and burning fats and ketones is far more efficient, inducing far less oxidative stress, than burning carbs. So, a foundational dietary strategy to optimize your mitochondrial health and live longer, and healthier, is to eat the right fuel. Once you become an efficient fat burner, you minimize the oxidative stress placed on your mitochondria, which is key.

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