People who previously had COVID-19 were more likely to experience swollen lymph nodes after their first dose of Pfizer's vaccine compared to those without a prior documented infection, according to a new study.
Researchers in the U.K. looked at adverse events after COVID-19 vaccination with 947 health care workers across three hospitals. Participants self-reported symptoms after vaccination. Of those, 265 participants had previously tested positive for the virus.
Overall, those who previously contracted COVID-19 were more likely to report at least one moderate to severe symptom compared to those without a prior infection. Researchers noted that those in the previous COVID-19 group were significantly more likely to experience lymphadenopathy, or swollen lymph nodes, as well as fever, fatigue, myalgia and arthralgia.
The study showed that about 4% of participants with a COVID-19 history experienced lymphadenopathy, compared to less than 1% of those who weren't infected.
SOURCES:
Becker’s Hospital Review April 29, 2021
MedRxiv April 22, 2021