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What You Need to Know About ‘Original Antigenic’ Sin and Fall COVID Shots

COVID-19 has been going on for nearly three years, and with another set of COVID booster shots ready to roll out, some scientists are taking a step back, cautioning that there still are some unanswered questions on how the shots work. They say more research needs to be done on what is known as “original antigenic sin,” meaning how the body’s immune system responds to repeated introductions of the COVID variants. Also known as immune imprinting, the frequent boosting —...

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