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Brussels Sprouts, Broccoli Block Breast Cancer Growth

I wrote about the benefits of broccoli sprouts many years ago, and now researchers have found even more benefits associated with cruciferous vegetables, an incredibly inexpensive and healthy source of nutrients.

A well-known anti-cancer compound found in broccoli, brussels sprouts, kale and other cruciferous vegetables -- sulforaphane (SUL) -- has been found to be effective in disrupting late stages of cell growth in breast cancer, according to a recent study.

Researchers discovered how SUL can block late stages of the cancer process by disrupting components of the cell called microtubules. Within hours, SUL blocked cell division and disrupted microtubules, which are long, slender cylinders made up of tubulin (protein), that are essential for the separation of duplicated chromosomes during cell division.

Scientists are unsure at this juncture if the doses required to produce the inhibition of tubulin polymerization are higher than those achievable via dietary intakes.

SUL is not an unknown compound to cancer researchers, however. Previous reports have shown that SUL induces defensive mechanisms that are effective in protecting normal cells from the initiation of cancer. More than a decade ago, scientists at Johns Hopkins University found SUL to be a potent inducer of enzyme systems that can defend against carcinogens.

Yahoo News September 16, 2004

Eurekalert

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