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Breast Inflammation is Key to Cancer Growth

Researchers have finally proven a long-held theory -- breast Inflammation is key to the development and progression of breast cancer. Scientists say they can now show that an inflammatory process within the breast itself promotes growth of breast cancer stem cells.

Inactivating this inflammation selectively was also shown to reduce the activity of these stem cells, and stopped breast cancer from forming.

Science Daily reports:

"Although inflammation ... has long been thought to be important in breast cancer development, the theory had been untestable because [the NFKB inflammatory pathway] is essential to embryonic development ... [This problem was addressed] by creating a mouse in which the inflammatory system within the adult animal's normal breast could be regulated. This allows selective inactivation of NFKB in different cell types and took 12 years to accomplish".

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